Stay in low-online mode, drop minimums to 1-2, widen brackets, add bots as filler, and shrink wing minimums so tiny groups enter group content.

-- Stay in the low-online queue set (ConfigureMatchmaker defaults already do this):
cvars.mm_lowOnlineLo = 250
cvars.mm_lowOnlineHi = 300
-- Let small groups start brawls (each brawl template, e.g.):
-- minPlayers = 2, maxExpandTime = 0
-- Fill with bots (ConfigureMatchmaker + ConfigureDediServer):
cvars.mm_botsCount = 12
cvars.sv_kickExcessiveBotsEnabled = 0
-- Tiny wings enter sector/league content (ConfigureShard + queue specials):
cvars.mm_sectorMinWingSize = 2
cvars.mm_raidMinWingSize = 2
cvars.mm_raidSquadFilter = 0
-- (in sectorQueue/leagueQueue specials: minSizeWing = 2, minSizeTeam = 1)
Also widen one arcade and one coop bracket to ranks 1-17 / MMV 0-99 so there is always an eligible queue, and set regionLocalizedTimeInQueue = 1 (already default) so regions never stall launches.
Additional Notes: 

Edit the low-online (Lo) templates; that set serves small servers.

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